The Clem Jones Centre for Neurobiology and Stem Cell Research
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About Us
The Clem Jones Centre for Neurobiology and Stem Cell Research creates therapies to treat injuries and diseases of the nervous system.
Our Highlights
- Spinal Injury Project: our preclinical research has demonstrated efficacy of the cellular nerve bridges for repairing spinal cord injury. Due to this success, we are now planning to proceed to human Phase I/2a clinical trial.
- Intensive rehabilitation trials: as part of the Spinal Injury Project, we have completed two clinical trials testing the safety, acceptability and feasibility of long-term intensive rehabilitation for people living with chronic spinal cord injury. These trials showed that the rehabilitation program was safe and that there was high compliance and acceptance by the participants.
- Peripheral Nerve Repair Project: the preclinical research has demonstrated that the cellular nerve bridges integrate into injured nerves in animal models and that there are associated improvements in expression of key molecules important for nerve repair. The nerve bridges are now being integrated with commercially available scaffolds to enhance repair outcomes.
- Neurodegeneration Project: Our preclinical research has demonstrated that the bacterium Chlamydia pneumoniae when applied within the nose can rapidly penetrate the olfactory (sense of smell) nerve, enter the brain and initiate molecular changes consistent with Alzheimer’s disease in animal models. This work and publication received international recognition with extensive media coverage. Due to this work, we are now establishing a world-first Smell Clinic for early detection of Alzheimer’s disease.
Page last updated: 21 Nov 2023, 12:53 PM